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We report the case of a sixteen-year-outdated affected individual from a non-consanguineous marriage. He was admitted for the medical center for investigation of the stature-ponderal hold off. The interrogation exposed intrauterine growth retardation with very low birth weight and profound mental retardation (IQ < 70) evolving given that birth. The affected individual also has a delay in psychomotor progress, strolling, and closure with the anterior fontanel without feeding on problems or hypoglycemia. There is absolutely no equivalent circumstance inside the relatives, and there is no family background of thyroid ectopy or hypothyroidism.